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Things That Bug Us

Some poor, hapless bug meandered onto the front porch the other day—no easy feat, since the porch is totally screened in—and, just its luck, met up with three kittens. It was one of those roundish, hard-shelled bugs and turned out to make a perfect hockey puck. The kittens were having a blast batting it around among themselves, but I daresay the bug was not as thrilled as being turned into a plaything as the kittens were in discovering a new toy. Read More “Things That Bug Us”

Blast It! Starting on Multiple Meds Makes Sense

Skimming through the latest edition of the diaTribe newsletter, my interest perked up when I read a report on the Banting Lecture by Dr. Ralph DeFronzo of the University of Texas Health Science Center and recipient of the 2008 Banting Medal for Scientific Achievement. In particular, his criticism of the American Diabetes Association’s treatment guidelines, “which recommend lifestyle changes and metformin as initial therapy for Type 2 diabetes,” jumped out at me. Read More “Blast It! Starting on Multiple Meds Makes Sense”

Tight Control and Cardiovascular Disease (Part 3): VADT

The VA Diabetes Trial, or VADT, was the third large study of tight blood glucose control and cardiovascular disease (CVD) risk in Type 2 diabetes that was presented at the June 2008 ADA Scientific Sessions. You can read about the results of the other two major studies in this vein, ADVANCE and ACCORD, in "Tight Control and Cardiovascular Disease (Part 1): ADVANCE" and "Tight Control and Cardiovascular Disease (Part 2): ACCORD." Read More “Tight Control and Cardiovascular Disease (Part 3): VADT”

Tight Control and Cardiovascular Disease (Part 2): ACCORD

This is my second report on the large studies of tight blood glucose control and cardiovascular disease risk in Type 2 diabetes that were presented at the ADA Scientific Sessions earlier this month. You can read about the results of the ADVANCE trial in "Tight Control and Cardiovascular Disease (Part 1): ADVANCE." This week, I’ll discuss the Action to Control Cardiovascular Risk in Diabetes, or ACCORD, trial. Read More “Tight Control and Cardiovascular Disease (Part 2): ACCORD”

Tight Control and Cardiovascular Disease (Part 1): ADVANCE

Three large studies presented at the American Diabetes Association’s (ADA) Scientific Sessions meeting in the last week have shed some light on the question of whether tight control of blood glucose levels helps prevent cardiovascular disease (CVD) in people with Type 2 diabetes. None of the trials found that tight control was associated with a lower risk of CVD, and one found an increased risk of death among the participants practicing more intensive control. Read More “Tight Control and Cardiovascular Disease (Part 1): ADVANCE”

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