What is one advantage of taking NPH insulin at bedtime?

Taking NPH insulin at bedtime can help reduce the rise in blood glucose that often occurs in the early morning hours, sometimes called the dawn phenomenon. Because NPH has a noticeable peak several hours after injection, its timing may need to be adjusted so that its strongest effect occurs overnight. Working with your healthcare provider can help ensure that the dose and timing match your body’s needs while minimizing the risk of low blood glucose.