Analgesics and Kidney Health

September 1, 2009 4:33 pm

Over-the-counter analgesics, such as aspirin, acetaminophen, ibuprofen, ketoprofen, and naproxen, are usually safe when taken as directed. However, if taken in excess or over too long a period of time, they can harm the kidneys. According to the National Kidney Foundation, as many as 3% to 5% of new cases of chronic kidney failure each year may be caused by the overuse of these painkillers. Products in which two or more painkillers are combined may be especially harmful to kidneys when used to excess.

The National Kidney Foundation recommends that these products be used only under a doctor’s supervision in people with kidney disease, heart disease[1], high blood pressure[2], or liver disease; in people over 65; or in people taking diuretics. Their effects can be monitored through a number of simple blood tests, such as BUN (blood urea nitrogen) and serum creatinine levels. Sometimes a urine test is used to check for protein in the urine (a sign of kidney damage as well as diseases such as diabetic nephropathy[3]). The National Kidney Foundation offers other tips for the safe use of analgesics:


  1. heart disease:
  2. high blood pressure:
  3. nephropathy:

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