Type 2 Study Looking for Volunteers

If you’ve been diagnosed with Type 2 diabetes[1] within the past five years, then you may be eligible to help researchers test treatments in a study sponsored by the National Institutes of Health (NIH).

Current guidelines typically recommend the oral drug metformin as a first-line treatment, along with a healthful diet and exercise. If metformin isn’t enough to control a person’s blood glucose levels, doctors will sometimes add another medicine, but no long-term studies have been conducted to determine which combination of drugs works best and has the fewest side effects.

To address this, NIH has launched a long-term clinical trial known as the GRADE study, in which investigators will examine the pros and cons of using common diabetes medicines along with metformin.


The study aims to enroll about 5,000 volunteers in 37 locations across the United States. All participants will take metformin, along with a second medicine randomly assigned from among four classes of drugs approved for use with metformin by the FDA.

Volunteers will receive their medicine for free during the study. Other health-care must come from their usual providers.

For more information about the study, including locations of participating centers, click here[2].

This blog entry was written by Web Editor Diane Fennell.

  1. Type 2 diabetes: https://www.diabetesselfmanagement.com/articles/diabetes-defintions/type-2-diabetes
  2. click here: https://grade.bsc.gwu.edu/web/grade/home?p_p_id=58&p_p_lifecycle=0&_58_redirect=%2F

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