Oral Insulin Study for Those at Risk of Type 1

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Do you have Type 1 diabetes? If so, your relatives may be interested in an actively recruiting TrialNet study that is testing whether oral insulin can prevent or delay the development of Type 1 in people who are at increased risk of the condition.

Type 1 Diabetes TrialNet is “an international network of researchers who are exploring ways to prevent, delay, and reverse the progression of Type 1 diabetes.” Type 1 is an autoimmune condition in which the body’s immune system creates proteins, known as antibodies, that destroy the insulin-producing beta cells of the pancreas. People who have relatives with Type 1 are at increased risk of developing the condition themselves.

To determine whether oral insulin, or insulin taken by mouth, can delay or prevent the development of Type 1, researchers are recruiting people who are from 3 to 45 years of age and have a brother, sister, child, or parent with Type 1 diabetes or people who are from 3 to 20 years of age who have a cousin, aunt, uncle, niece, nephew, half sibling, or grandparent with Type 1.

Participants will be randomly assigned to take either one capsule of oral insulin or one capsule of placebo (inactive substance) each day (they will not know which group they belong to) and will be given blood tests at the study center every six months and at other times as needed.

For more information, and to see if you might be eligible for the study, click here.

This blog entry was written by Web Editor Diane Fennell.

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