FDA Approves Qternmet XR, New Type 2 Diabetes Combo Pill

The U.S. Food and Drug Administration (FDA) has approved Qternmet XR extended-release tablets as an adjunct treatment to diet[1] and exercise[2] in adults with type 2 diabetes[3]. According to a press release from manufacturer AstraZeneca[4], the oral medicine is a combination of the SGLT2 inhibitor[5] dapagliflozin, the DPP-4 inhibitor[6] saxagliptin and metformin extended-release.

The approval was based on the results of two phase 3 trials[7] evaluating different combinations of dapagliflozin and saxagliptin on a base of metformin over 24 weeks.

Want to learn more about SGLT2 inhibitors, DPP-4 inhibitors and metformin? Read “Diabetes Medicine: SGLT2 Inhibitors,”[8] “Diabetes Medicine: DPP-4 Inhibitors”[9] and “What to Know About Metformin.”[10]

  1. diet: https://www.diabetesselfmanagement.com/nutrition-exercise/meal-planning/
  2. exercise: https://www.diabetesselfmanagement.com/nutrition-exercise/exercise/
  3. type 2 diabetes: https://www.diabetesselfmanagement.com/diabetes-resources/definitions/type-2-diabetes/
  4. press release from manufacturer AstraZeneca: https://www.astrazeneca.com/media-centre/press-releases/2019/qternmet-xr-approved-in-the-us-for-the-treatment-of-type-2-diabetes-03052019.html
  5. SGLT2 inhibitor: https://www.diabetesselfmanagement.com/blog/diabetes-medicine-sglt2-inhibitors/
  6. DPP-4 inhibitor: https://www.diabetesselfmanagement.com/blog/diabetes-medicine-dpp-4-inhibitors/
  7. phase 3 trials: https://www.fda.gov/patients/drug-development-process/step-3-clinical-research
  8. “Diabetes Medicine: SGLT2 Inhibitors,”: https://www.diabetesselfmanagement.com/blog/diabetes-medicine-sglt2-inhibitors/
  9. “Diabetes Medicine: DPP-4 Inhibitors”: https://www.diabetesselfmanagement.com/blog/diabetes-medicine-dpp-4-inhibitors/
  10. “What to Know About Metformin.”: https://www.diabetesselfmanagement.com/blog/what-to-know-about-metformin/

Source URL: https://www.diabetesselfmanagement.com/blog/fda-approves-qternmet-xr-new-type-2-diabetes-combo-pill/

Diane Fennell: Diane Fennell has been an editor at Diabetes Self-Management magazine since 2003. She is currently the Editorial Director. (Diane Fennell is not a medical professional.)

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