Don’t Call My Liver Fat!


Isn’t there enough to contend with having diabetes? You need to take care of your eyes[1], feet[2], heart[3]… Now you have to worry about your liver? Well, yes. Fatty liver disease may be something you’re not all that familiar with, but if you have Type 2 diabetes[4], it’s a good idea to know about this. Hence this week’s posting!

Liver 101
Let’s back up for a minute and talk about your liver. The liver is one of the largest organs in the body, weighing about three pounds. It’s located in the right upper abdomen, below the diaphragm. It’s pretty amazing what the liver does, if you stop and think about it. Here’s a brief run-down:

• Detoxifies harmful substances
• Produces proteins that help blood to clot
• Breaks down fat for energy
• Makes bile (which is needed for fat breakdown)
• Helps keep blood glucose levels constant
• Metabolizes protein
• Stores vitamins and minerals

Given all that the liver does, you can see why it’s so important to keep it in shape.

Fatty liver disease
The actual name of this condition is non-alcoholic fatty liver disease, or NAFLD, for short. This is a condition in which extra fat builds up in liver cells, and, as the name implies, it’s not due to drinking alcohol (that’s a whole other issue). The liver normally contains some fat, but if more than 5% to 10% of the liver’s weight is due to fat, you’ve got a fatty liver.

Who gets NAFLD? It’s most common in people who:

• Are overweight or obese
• Have Type 2 diabetes
• Have high blood cholesterol or triglycerides
• Are losing weight quickly
• Have poor eating habits

NAFLD can run in the family. It may also be caused by certain medicines and viral hepatitis. But according to the American Liver Foundation, some people have NAFLD and have no risk factors. It’s the most common cause of liver disease in the US and affects up to 25% of people in the United States. NAFLD is also a leading cause of end-stage liver disease requiring liver transplantation (other causes include hepatitis and alcohol abuse). If not treated, this disease can lead to swelling of the liver, cirrhosis, liver cancer, or liver failure.

NAFLD symptoms
NAFLD usually causes no symptoms in the early stages of the disease. Symptoms may occur as the disease progresses, and include fatigue, weakness, weight loss, yellowing of the skin and eyes, itching, fluid buildup, and confusion. A person may feel pain in the right upper part of the abdomen and have patches of dark skin on the neck or under the arms.

NAFLD may be diagnosed during a regular physical exam. Your provider may notice that your liver is enlarged. Or you might report that you’ve been having right upper quadrant pain. Liver enzymes may be checked through a blood test (high levels are suspicious), and a fatty liver can show up on an ultrasound. A definitive diagnosis is made by having a liver biopsy, which can detect extra fat, inflammation, and damaged liver cells.

There’s no medical treatment for NAFLD at this time. The thiazolidinedione drugs[5] Avandia (rosiglitazone) and Actos (pioglitazone) have been shown to reduce fat in the liver, but these are not FDA-approved to be used for NAFLD. However, as with diabetes, lifestyle changes can help. Losing weight (if you need to), controlling your blood glucose and cholesterol levels, cutting down on refined carbohydrate foods, getting more physical activity, and avoiding alcohol all can help prevent the condition from worsening and, in the early stages, may even reverse NAFLD. In addition, talk with your provider before taking certain medicines or dietary supplements, as some can be harmful to the liver.

Do what you can to keep your liver healthy. Talk to your health-care provider to learn more or if you have any of the symptoms previously mentioned.

  1. eyes:
  2. feet:
  3. heart:
  4. Type 2 diabetes:
  5. thiazolidinedione drugs:

Source URL:

Amy Campbell: Amy Campbell is the author of Staying Healthy with Diabetes: Nutrition and Meal Planning and a frequent contributor to Diabetes Self-Management and Diabetes & You. She has co-authored several books, including the The Joslin Guide to Diabetes and the American Diabetes Association’s 16 Myths of a “Diabetic Diet,” for which she received a Will Solimene Award of Excellence in Medical Communication and a National Health Information Award in 2000. Amy also developed menus for Fit Not Fat at Forty Plus and co-authored Eat Carbs, Lose Weight with fitness expert Denise Austin. Amy earned a bachelor’s degree in nutrition from Simmons College and a master’s degree in nutrition education from Boston University. In addition to being a Registered Dietitian, she is a Certified Diabetes Educator and a member of the American Dietetic Association, the American Diabetes Association, and the American Association of Diabetes Educators. Amy was formerly a Diabetes and Nutrition Educator at Joslin Diabetes Center, where she was responsible for the development, implementation, and evaluation of disease management programs, including clinical guideline and educational material development, and the development, testing, and implementation of disease management applications. She is currently the Director of Clinical Education Content Development and Training at Good Measures. Amy has developed and conducted training sessions for various disease and case management programs and is a frequent presenter at disease management events.

Disclaimer of Medical Advice: You understand that the blog posts and comments to such blog posts (whether posted by us, our agents or bloggers, or by users) do not constitute medical advice or recommendation of any kind, and you should not rely on any information contained in such posts or comments to replace consultations with your qualified health care professionals to meet your individual needs. The opinions and other information contained in the blog posts and comments do not reflect the opinions or positions of the Site Proprietor.