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Dapagliflozin Improves Blood Glucose in Type 1 Diabetes

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Dapagliflozin Improves Blood Glucose in Type 1 Diabetes

Treatment with the oral diabetes drug dapagliflozin (a member of the class of medicines known as SGLT2 inhibitors) for 24 weeks improves blood glucose control in people with type 1 diabetes, according to a new study in Diabetes Care.

For the research, roughly 1,600 people with inadequately controlled type 1 diabetes received 5-milligram or 10-milligram doses of dapagliflozin or placebo (inactive treatment). The researchers found that those receiving dapagliflozin experienced improved average blood glucose levels, time in range and blood glucose variability.

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“The reduced variability reported here suggests that treatment with dapagliflozin along with adjustable insulin may improve treatment adherence and reduce the risk of complications in people with type 1 diabetes,” the researchers noted.

The European Commission recently approved dapagliflozin for use as an adjunct treatment in type 1 diabetes in certain adults, and the medicine is currently under review in the United States for use along with insulin in type 1 diabetes.

Want to learn more about dapagliflozin and other members of this drug class? Read “Diabetes Medicines: SGLT2 Inhibitors.”

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