Cardiovascular Biomarker Tests

One or more of these laboratory test may be prescribed by your health-care provider to provide additional information when “classic” risk factors for heart disease leave the picture unclear. For the most accurate test results, be sure to follow exactly any instructions your health-care provider gives regarding test procedures. Note that the laboratory reference ranges may vary slightly from one lab to the next.

Test name: High-sensitivity C-reactive protein (hsCRP or CRP)
Preparation for test: None
Required sample: Blood sample
Results: Reference range: 0.0–0.5 mg/l; Low risk: <1 mg/l; Average risk 1–3 mg/l; High risk: >3 mg/l

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Test name: B-type natriuretic peptide (BNP)
Preparation for test: None
Required sample: Blood sample
Results: Reference range 0–100 pg/ml

Test name: Albumin-to-creatinine ratio (ACR)
Preparation for test: None
Required sample: Urine sample (May be random, timed, or collected over 24 hours)
Results: Normal <30 mg/g; Microalbuminuria: >30 mg/g

Test name: Plasminogen activator inhibitor-1 (PAI-1)
Preparation for test: Fast for 8–12 hours before test
Required sample: Blood sample
Results: Normal 3–72 ng/ml

Test name: Adiponectin
Preparation for test: None
Required sample: Blood sample
Results: Reference range: 4–22 mcg/ml (female); 2–26 mcg/ml (male)