Diabetes Self-Management Blog

We have previously written about the multiple health benefits of metformin (brand name Glucophage and others), an oral drug used to treat Type 2 diabetes: Beyond controlling blood glucose levels, this medicine has been linked to a decreased risk of death in people with Type 2, a lowered cancer risk, and possibly an increased life span.

Now, a new study in rats suggests that there may be even more good news about metformin, this time in the area of heart health. Cardiovascular disease is the leading cause of death for people with diabetes.

Researchers at the University of Gothenburg Sahlgrenska Academy in Sweden assigned rats with high blood pressure and insulin resistance to receive either 100 milligrams per kilogram of body weight per day of metformin, 2 milligrams per kilogram per day of rosiglitazone (Avandia), or no drug over the course of 12 months. (Ten rats without health conditions served as a control group.)

At the end of the study period, the researchers found that the rats treated with metformin had improved heart pumping capacity, improved heart efficiency (defined by a greater ability to convert energy into mechanical work), lowered fat accumulation in the heart, and a reduced loss of heart cells. Rosiglitazone did not have any positive effects on heart health.

“The animals in our study were treated with metformin for a whole year, so the effect seems to persist,” noted lead researcher Jörgen Isgaard.

For more information, see the article “Diabetes Drug Can Prevent Heart Disease, New Study Suggests,” or see the study’s abstract from the journal Diabetes.

This blog entry was written by Web Editor Diane Fennell.

POST A COMMENT       
  

We are currently experiencing technical difficulties with our commenting system. Thank you for your patience as we work to resolve them.


What We're Reading
JDRF 2015 Children's Congress (11/17/14)
Diabetes Self-Management Readers' Poll: Support Groups (11/20/14)
Diabetes Self-Management Readers’ Poll: Daylight Saving Time (11/10/14)
World Diabetes Day (11/14/14)

Heart Health
Self-Manage Your Blood Pressure (09/02/14)
Pistachios Offer Protection for People With Diabetes (08/29/14)
Which Butter (or Spread) Is Better? (07/28/14)
High-Salt Diet Doubles Heart Risk in Type 2 Diabetes (07/25/14)

Diabetic Complications
You Can Fight Chronic Pain With Food (11/10/14)
Mediterranean Diet May Benefit Kidneys (11/06/14)
Statins May Reduce Risk of Nerve Damage, Other Diabetes Complications (09/18/14)
New Approach for Neuropathy Pain? (08/18/14)

Diabetes Research
A Diabetes Cure in Mice (11/13/14)
Mediterranean Diet May Benefit Kidneys (11/06/14)
Can Grapefruit Juice Prevent Weight Gain, Increase Insulin Sensitivity? (10/16/14)
Low-Carb Diet Improves Quality of Life in Type 2 Diabetes (10/07/14)

 

 

Disclaimer of Medical Advice: You understand that the blog posts and comments to such blog posts (whether posted by us, our agents or bloggers, or by users) do not constitute medical advice or recommendation of any kind, and you should not rely on any information contained in such posts or comments to replace consultations with your qualified health care professionals to meet your individual needs. The opinions and other information contained in the blog posts and comments do not reflect the opinions or positions of the Site Proprietor.