To print: Select File and then Print from your browser's menu
Knocking Out Prediabetes
July 25, 2008
If you are one of the more than 56 million Americans who have prediabetes, more guidance on how reduce your risk of Type 2 diabetes may be on the way. This week, the American Association of Clinical Endocrinologists (AACE) agreed to recommend an aggressive approach to treating prediabetes, releasing the first official treatment recommendations that have been made for this condition.
What Is Prediabetes?
The AACE now recommends a “two-pronged approach” for preventing the conversion of prediabetes to diabetes and lowering cardiovascular risk.
Step 1: Diet, Exercise…and Drugs?
The DPP, a study published in 2002 that involved more than 3,000 people with prediabetes, showed that losing 5% to 7% of their body weight lowered people’s risk of Type 2 diabetes by 58% over three years. The participants lost weight by dieting (cutting fat and calories) and exercising moderately (walking was the most popular exercise) for at least 150 minutes a week (about 20 minutes a day). You can read more details about the DPP at http://diabetes.niddk.nih.gov/dm/pubs/preventionprogram.
The AACE experts also agreed that certain drugs may play a role in treating prediabetes if diet and exercise do not lower people’s blood glucose levels enough. In the DPP, the diabetes drug metformin (Glucophage and other brand names) was shown to help prevent Type 2 diabetes in people with prediabetes, though not as effectively as diet and exercise. A more recent study of 602 people, presented at the American Diabetes Association Scientific Sessions in June, found that people with prediabetes who took pioglitazone (Actos) were 81% less likely to develop full-blown diabetes over three years compared to people who took a placebo drug. However, the pioglitazone group did gain more weight than the placebo group (about 8 pounds vs. 2 pounds). The study was sponsored by pioglitazone manufacturer Takeda. As of now, no drugs are officially approved for the treatment of prediabetes.
Step 2: Reduce Cardiovascular Risk
What Else Can You Do?
If you have prediabetes, talk to your health-care provider about aggressively taking steps to prevent Type 2 diabetes. And if you think you may have prediabetes, get tested and encourage other people who may be at risk to do the same.
Disclaimer of Medical Advice:You understand that the blogs posts and comments to such blog posts (whether posted by us, our agents, bloggers, or by users) do not constitute medical advice or recommendation of any kind and you should not rely on any information contained on such posts or comments to replace consultations with your qualified health care professionals to meet your individual needs. The opinions and other information contained in the blog posts and comments do not reflect the opinions or positions of the Site Proprietor.