Diabetes Self-Management Blog

Are you one of the more than 79 million Americans who is estimated to have prediabetes? Then you may be interested in participating in a large study that is currently enrolling volunteers to determine whether vitamin D supplementation can prevent Type 2 diabetes.

The Vitamin D and Type 2 Diabetes (D2d) study is the first large-scale trial that will examine whether daily supplementation with 4,000 International Units (IUs) of vitamin D3 (cholecalciferol) can prevent or delay the development of Type 2 diabetes in people age 30 or older who have prediabetes (a condition in which blood glucose levels are higher than normal, but not high enough to be diagnosed as diabetes). The typical adult intake of vitamin D is 400 to 600 IUs per day.

The researchers aim to enroll roughly 2,500 people, half of whom will receive vitamin D and half of whom will receive placebo (an inactive treatment). Participants will have check-ups related to the study twice a year and will receive regular health care through their usual providers.

The study will be double-blind, meaning that neither the participants nor the researchers will know who is receiving the vitamin D and who is receiving the placebo. The research will continue until enough people have developed Type 2 diabetes that a scientifically valid comparison between the two groups can be made — likely about four years.

“Vitamin D use has risen sharply in the US in the last 15 years, since it has been suggested as a remedy for a variety of conditions, including prevention of Type 2 diabetes. But we need rigorous testing to determine if vitamin D will help prevent diabetes. That’s what D2d will do,” said Myrlene Staten, MD, D2d project officer.

Clinical study sites are located at approximately 20 locations across the United States. To learn more about the research, including how to enroll, visit the official D2d Web site.

This blog entry was written by Web Editor Diane Fennell.


  1. After I was diagnosed type 2 by my primary, an endocrinologist tested me for low vitamin D levels. It was extremely low. She told me that she mainly checked because she herself (type 1 diabetic) had a chronic problem with low vitamin D, but she never mentioned a potential connection with low D and pre-diabetes.

    Posted by Joe |

Post a Comment

Note: All comments are moderated and there may be a delay in the publication of your comment. Please be on-topic and appropriate. Do not disclose personal information. Be respectful of other posters. Only post information that is correct and true to your knowledge. When referencing information that is not based on personal experience, please provide links to your sources. All commenters are considered to be nonmedical professionals unless explicitly stated otherwise. Promotion of your own or someone else's business or competing site is not allowed: Sharing links to sites that are relevant to the topic at hand is permitted, but advertising is not. Once submitted, comments cannot be modified or deleted by their authors. Comments that don't follow the guidelines above may be deleted without warning. Such actions are at the sole discretion of DiabetesSelfManagement.com. Comments are moderated Monday through Friday by the editors of DiabetesSelfManagement.com. The moderators are employees of Madavor Media, LLC., and do not report any conflicts of interest. A privacy policy setting forth our policies regarding the collection, use, and disclosure of certain information relating to you and your use of this Web site can be found here. For more information, please read our Terms and Conditions.

What We're Reading
Take Part in the Big Blue Test! (10/15/14)
Free Webinar on Detecting Health-Care Errors and Fraud (10/17/14)
Ski and Snowboard Camps for Kids With Diabetes (10/06/14)
Project Blue November (10/06/14)

Type 2 Diabetes
Discovering I Had Type 2 Diabetes (10/17/14)
Low-Carb Diet Improves Quality of Life in Type 2 Diabetes (10/07/14)
Long Hours at Low-Income Jobs Linked to Increased Diabetes Risk (10/02/14)
Metformin Study Currently Recruiting (08/19/14)



Disclaimer of Medical Advice: You understand that the blog posts and comments to such blog posts (whether posted by us, our agents or bloggers, or by users) do not constitute medical advice or recommendation of any kind, and you should not rely on any information contained in such posts or comments to replace consultations with your qualified health care professionals to meet your individual needs. The opinions and other information contained in the blog posts and comments do not reflect the opinions or positions of the Site Proprietor.

Blood Glucose Self-Monitoring — Part 3: Smart Monitoring

10 Keys to Long-Term Weight Loss

Take Your Best Shot: Stay Up to Date on Vaccines

Complete table of contents
Subscription questions